|
Symbol Name ID |
Prnp
prion protein MGI:97769 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
thymus atrophy |
thymus hypoplasia |
decreased thymocyte number |
decreased DN2 thymocyte number |
decreased DN4 thymocyte number |
increased DN3 thymocyte number |
abnormal T cell differentiation |
increased double-negative T cell number |
decreased double-positive T cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased CD8-positive, alpha-beta T cell number |
increased gamma-delta T cell number |
abnormal B cell morphology |
microgliosis |
abnormal susceptibility to prion infection |
decreased susceptibility to prion infection |
increased susceptibility to prion infection |
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| Availability | Mouse Genotype | |||||||||||||||||||
| Prnp/Prndtm1Aag/Prnp/Prndtm1Aag | * | |||||||||||||||||||
| Prnpa/Prnpa | ||||||||||||||||||||
| Prnpb/Prnpb | ||||||||||||||||||||
| Prnpc/Prnpc | ||||||||||||||||||||
| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp)a19Cwe/0 |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp)a20Cwe/0 |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp)c35Cwe/0 |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp)37Jcol/? |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp)46Jcol/? |
* | |||||||||||||||||||
| Prnptm1Cwe/Prnptm1Cwe Tg(Lck-Prnp)33Cwe/0 |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp)4053Sbp/0 |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Prnp*S170N*N174T)1020Aag/0 |
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| Prnptm1Edin/Prnptm1Edin | ||||||||||||||||||||
| Prnptm1Lnq/Prnptm1Lnq | ||||||||||||||||||||
| Prnptm1Miy/Prnptm1Miy | ||||||||||||||||||||
| Prnptm1Rcm/Prnptm1Rcm | ||||||||||||||||||||
| Prnptm2Lnq/Prnptm2Lnq | * | |||||||||||||||||||
| Prnptm1Tuzi/Prnp+ | ||||||||||||||||||||
| Prnptm1Tuzi/Prnptm2Edin | ||||||||||||||||||||
| Prnptm2Tuzi/Prnp+ | * | |||||||||||||||||||
| Prnptm2Tuzi/Prnptm2Edin | ||||||||||||||||||||
| Tg(Prnp)4053Sbp/0 | ||||||||||||||||||||
| Tg(Prnp)a20Cwe/0 | ||||||||||||||||||||
| Prnptm1Cwe/Prnptm1Cwe Tg(Nefh-cre)22Jcol/? Tg(Prnp)46Jcol/? (conditional) |
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| Prnptm1Cwe/Prnptm1Cwe Tg(Nefh-cre)22Jcol/? Tg(Prnp)37Jcol/? (conditional) |
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| Prnptm1Tuzi/Prnp+ Tg(CMV-cre)1Cgn/? (conditional) |
* | |||||||||||||||||||
| Prnptm1Tuzi/Prnptm2Edin Tg(CMV-cre)1Cgn/? (conditional) |
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| Prnptm2Tuzi/Prnp+ Tg(CMV-cre)1Cgn/? (conditional) |
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| Prnptm2Tuzi/Prnptm2Edin Tg(CMV-cre)1Cgn/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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